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Zoology - Applications of Biotechnology Practice Question Paper

12th Standard EM

    Reg.No. :
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Biology

Time : 01:00:00 Hrs
Total Marks : 40
    6 x 1 = 6
  1. The genetic defect adenosine deaminase deficiency may be cured permanently by

    (a)

    Enzyme replacement therapy

    (b)

    periodic infusion of genetically engineered lymphocytes having ADA cDNA

    (c)

    administering adenosine deaminase activators

    (d)

    introducing bone marrow cells producing ADA into embryo at an early stage of development.

  2. The first synthetic vaccine produced was_________

    (a)

    DPT

    (b)

    HbsAg

    (c)

    Measles

    (d)

    Polio

  3. This is not the advantage of new generation vaccine

    (a)

    They trigger immune response only against not specific pathogens

    (b)

    They produce target proteins

    (c)

    They produce long lasting immunity

    (d)

    They are with less toxic effect

  4. PCR was developed by___________

    (a)

    Engvall

    (b)

    Kary Mullis

    (c)

    Anderson

    (d)

    Ian wilmut

  5. Statement 1: Rosie was the first transgenic goat.
    Statement 2: Meat is enriched with human protein

    (a)

    Statement 1 is true. Statement 2 is false

    (b)

    Satement 1 is false. Statement 2 is true

    (c)

    Both statements I and 2 are true

    (d)

    Both statements 1 and 2 are false

  6. Arrange the steps of PCR in proper sequence

    (a)

    Denaturation, Primer extension, Renaturation

    (b)

    Renaturation, Denaturation, Primer extension

    (c)

    Primer extension, Denaturation, Renaturati

    (d)

    Denaturation, Renaturation, Primer extension

  7. 1 x 1 = 1
  8. In mammals embryonic stem cells are
    I. Totipotent
    II. Pleuripotent
    III. Multipotent
    IV. Oligopotent
    V. Unipotent
    (a) I, II, IV
    (b) II, IV, V
    (c) II, III
    (d) I, IV, V

    ()

    I, IV, V

  9. 1 x 2 = 2
  10. Assertion: It is possible to genetically engineer the organisms and produce vaccines.
    Reason: DNA vaccines are easy to produce.
    A. A and R are true, R is the correct explanation of A
    B. A and R are true, R is not the correct explanation of A
    C. A is true, R is false
    D. Both A and R are false

  11. 2 x 2 = 4
  12. Antiviral proteins produced by virus infected cells________

  13. Who coined the term biotechnology________

  14. 1 x 2 = 2
  15. Find out the incorrect statement about human alpha lactalbumin.
    (a) Rosie, the firsttransgenic cow produced milk enriched with a human alpha lactalbumin.
    (b) Transgenic E.coli are also produced which produce milk included with human alpha lactalbumin.
    (c) Human alpha lactalbumin is synthesized by the mammary glands of cow and human.
    (d) Human alpha lactalbumin possesses bactericidal and anti tumour activities

  16. 3 x 2 = 6
  17. What is genetically engineered Insulin?

  18. How has-recombinant DNA technology helped in treating haemophilia?

  19. Define cloning. Name the first organism developed by cloning.

  20. 3 x 3 = 9
  21. What are stem cells? Explain its role in the field of medicine

  22. What is a stem cell bank?

  23. State any two uniqueness of ELISA test.

  24. 2 x 5 = 10
  25. Mention the advantages and disadvantages of cloning.

  26. Describe the procedure by which Dolly was developed.

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