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Zoology - Molecular Genetics

12th Biology - Zoology - Molecular Genetics Practice Question Paper

Zoology - Molecular Genetics Practice Question Paper

12th Standard

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Biology

Time : 01:00:00 Hrs
Total Marks : 50
    8 x 1 = 8

  1. What is the basis for the difference in the synthesis of the leading and lagging strand of DNA molecules?

    (a)

    Origin of replication occurs only at the 5' end of the molecules

    (b)

    DNA ligase works only in the 3' → 5' direction

    (c)

    DNA polymerase can join new nucleotides only to the 3' end of the growing stand.

    (d)

    Helicases and single-strand binding proteins that work at the 5' end

  2. The first codon to be deciphered was ______ which codes for ________.

    (a)

    AAA, proline

    (b)

    GGG, alanine

    (c)

    UUU, Phenylalanine

    (d)

    TTT, arginine

  3. The classical concept of a gene was given by _______.

    (a)

    Mendel

    (b)

    Sutton

    (c)

    Johannsen

    (d)

    Hofmeister

  4. The term ___________ refers to DNA of Prokaryotes.

    (a)

    Nuclein

    (b)

    Ribozyme

    (c)

    Genophore

    (d)

    Nucleosome

  5. In genetic code there are __________ possible triplets.

    (a)

    62

    (b)

    61

    (c)

    68

    (d)

    64

  6. There are no tRNA, for _______ codons.

    (a)

    AUG

    (b)

    GUC

    (c)

    UAA

    (d)

    AGA

  7. Which one of the following pairs of codons is correctly matched with their function or the single for the particular amino acid?

    (a)

    GUU, GCU - Alanine

    (b)

    UAG, UGA - Stop codon

    (c)

    AUG, ACG - start/methionine

    (d)

    UUA, UCA - Leucine

  8. A nucleoside is composed of __________

    (a)

    Sugar and Phosphate

    (b)

    Nitrogen base and Phosphate

    (c)

    Sugar and Nitrogen base

    (d)

    Sugar, Phosphate and Nitrogenous base

    9. 1 x 1 = 1

  9. __________ number of codons, codes for cystine

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    Two

    10. 1 x 1 = 1

  10. (i) The RNA polymerase. opens up the DNA for replication
    (ii) There more than one tRNA for most amino acids.
    (iii) The split gene feature of eukaryote genes is absent in prokaryotes.
    (iv) The X chromosome is the smallest chromosome.
    (a) i and iv only
    (b) i and ii
    (c) ii and iii only
    (d) ii and iii

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    (c) ii and iii only

    11. 1 x 2 = 2

  11. Assertion: Both the strands of DNA can be copied during transcription.
    Reason: This will help to produce more RNA with different sequences
    Codes:
    A. A and R are true, Ris the correct explanation of A
    B. A and R are true, R is not the correct explanation of A
    C. A is true, R is false
    D. Both A and R are false

    12. 1 x 1 = 1

  12. There are no tRNA for stop codons.

    13. 1 x 2 = 2

  13. (a) 40 S
    (b) 70 S
    (c) 80 S
    (d) 60 S

    14. 1 x 2 = 2
  14. i. Southern blotting - Probe
    ii. β-gal - Lac operon
    iii. Replication fork - Ligase
    iv. Singer - TMR

    a) i and iii
    b) iii
    c) i
    d) ii

    15. 2 x 2 = 4

  15. The adjacent nucleotides of DNA are held together by_________ bonds.

  16. DNA finger printing involves identifying some specific differences in some specific regions in DNA called _________

    17. 1 x 2 = 2

  17. (i) Repetitive DNA sequences are called micro satellites.
    (ii) Hershey could prove that proteins are the infective part of a virus.
    (iii) Antibiotics inhibit stages of bacterial protein synthesis in pathogenic forms.
    (iv) DNA ➝ RNA ➝ proteins is the central dogma in molecular biology.
    (a) iii and iv
    (b) i only
    (c) i and iv only
    (d) ii only

    18. 3 x 2 = 6

  18. Name the parts marked ‘A’ and ‘B’ in the given transcription unit:

  19. What are the properties that a molecule must possess to act as genetic material?

  20. Mention any four areas where DNA fingerprinting can be used.

    21. 2 x 3 = 6

  21. Why the human genome project is called a mega project?

  22. What is S-D Sequence?

    23. 3 x 5 = 15

  23. a) Identify the figure given below
    b) Redraw the structure as a replicating fork and label the parts
    c) Write the source of energy for this replication and name the enzyme involved in this process.
    d) Mention the differences in the synthesis of protein, based on the polarity of the two template strands.

  24. Explain the properties of genetic material.

  25. Draw a flow chart depicting the steps of DNA fingerprinting technique.

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