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Published on: 28/05/2021
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Questions + Answers key
Take MCQ Biology Test1.
Study the given pedigree chart and answer the questions that follow.
(a) Is the trait recessive or dominant?
(b) Is the trait sex-linked or autosomal?
(c) Give the genotypes of the parents shown in generation I and their third child shown in generation II and the first grandchild shown in generation III.
2.
The traits are inherited through generations.This fact is based on the principles proposed by Gregor Mendel in 1865. However,Mendel dis not discovered these principles of inheritance by studying human beings then how his principles are applied in case of humans.
3.
Explain with an example, where a gene, which carries a major disadvantage in homozygous condition.
4.
A normal male marries a carrier female for haemophilia.What is the possibility of male child being haemophic and what is the probability of female carrier?what is the probability of female child infected?
5.
How many linkage groups are present in the organism whose genomic chromosome number is n=8?
6.
Determine the genotype of offsprings in a cross between normal male and female cockroaches.
7.
Whiich phenomenon strongly favours the linear arrangement of genes on the chromosomes?Define the phenomenon and give the situation where this phenomenon cannot occur.
8.
A man having blood group A is married with an woman having blood group B.work out the genotype of man and woman if their one of the children is born with blood group O.what is the possible genotype of other offsprings.
9.
Morgan(1910) made the following crosses in Drosophilla.Write the results of these crosses in F1 generation.
(a) The white eyed male was crossed with red eyed female.
(b) The females of F1 generation were crossed with red eyed males.
(c) White eyed females were crossed with red eyed males.
10.
Identify the phenomenon in the following example-
"Sickle cell anaemia is an autosomal recessive trait.It is caused by the substitution of anino acid glutamic acid by valine at the sixth position of the beta globin chain of haemoglobin.This substitution of amino acid occurs due to phenomenon in which the sixth codon of beta globin gene is transformed from GAG to GUG".
1.
(a) It is a dominant trait.
(b) It is autosomal.
(c) Genotypes of parents in generation I:
Female aa; male Aa.
Genotype of third child in generation II: Aa.
Genotype of first grandchild in generation III: Aa
2.
Mendel performed his experiments on pea plants,i.e pisum sativum.After eight years of tedious experiments with pea plants, he proposed three fundamental principles of inheritance.These principles eventually assisted clinicians in human disease research,e.g after a few years of the discovery of Mendel's work,Archibald Garrod applied Mendel's principles to his study of alkaptonuria.Today, Mendalwhether we talk about pea plants or humans,genetic traits that follow the rules of inheritanceMendel proposed are called Mendelian Principles.
3.
An example for this condition is sickle-anaemia. The person with homozygous condition (Hbs Hbs ) for sickle-cell anaemia does not survive beyond the age of 20 years.
The individual with normal gene (HbHb) does not have sickle-cell anaemia but they are sensitive towards malaria.
The person with heterozygous condition (HbHbs) for sickle-cell anaemia does not develop both sickle-cell anaemia and malaria.
Due to abnormal haemoglobin, the malarial parasite will not harm the person.
Hence, in this case, the heterozygous condition has more survival chances, an advantage with respect to the homozygous individuals.
4.

male sex is determined by Y-chromosome which does not bear the gene for haemophilia.In the given case, when a normal male marries a carrier female the resultant offsprings will be follows- this marriage results in the four types of offsprings in equal ratio i.e .,
Normal Girl with XX genotype
Normal boy with XY genotype
carrier Girl with XXh genotype
The defect of haemophilia does not appear in the girl carrier because the second X chromosome possesses therefore female child can be a carrier but does not develop diseases.The male child on the other hand can develop the disese.
5.
The number of linkage group in an organism corresponds to its haploid number of chromosomes.Therefore the number of linkage groups in the given organism is 8.
6.

In case of cockroaches the males have old sex chromosomes (AA + X)whereas the female have two homomorphic sex chromosomes(AA + XX) The male cockroach is heterogametic and produces two type of gemetes A+ X , A + O.The progeny is obtained in the ration of 50 male : 50 females.The genotype of offsprings 50% AA+XX and 50% AA+XO
7.
The phenomenon that strongly favours the linear arrangements of genes on the chromosomes, is linkage.linkage is the tendency for allells of different genes to pass together from the generation to the next.The genes located on different chromosomes cannot show any linkage.
8.
If man is homozygous-IAIA and woman is also homozygous -IBIB then the offsprings will be -IAIB

If the man is hetrozygous-IAIi and the woman - IBIi then the offsprings will be

Thus the genotypes of parents are
Man=IAIi woman=IBIi
genotypes of offsprings are-IAIB , IAIi ,IBIi and IiIi
9.
(a) All the flies of F1 generation were red eyed.
(b) It was a set a test cross and the result was 1 red eyed female : 1 white eyed female : 1 red eyed male : 1 white eyed male
(c) All the males were white eyed and all the females were red eyed.
10.
The phenomenon is point mutation that involves substitution of a single nitrogenous base in DNA.
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