The diagrammatic representation of position of genes and related distances between the adjacent genes is called gene mapping. 
Uses 
(i) Used to determine gene order.
(i) Identify the locus of a gene.
(i) Calculate the distance between genes.
(i) Useful in predicting results of dihybrid and trihybrid crosses.
(i) Allows the geneticists to understand the overall genetic complexity of particular organism.

Crossing over is a process that includes four stages.
1. Synapsis
(i) Pairing between two homologous chromosomes is initiated during sub stage zygotene stage of prophase I of meiosis I
(ii) Homologous chromosomes are aligned side by side resulting in the formation of bivalents. It also occurs in zygotene sub-stage of prophase I of meiosis I tetrads.This pairing phenomenon is called synapsis.
 2.Tetrad Formation
(i) Each homologous chromosome of a bivalent begin to form two identical sister chromatids.
(ii) They remain held together by a centromere at this stage each bivalent has four chromatids. This stage is called tetrad stage.
3. Cross Over
After tetrad formation, crossing over occurs in pachytene stage.
The non-sister chromatids of homologous pair make a contact at one or more points. These points of contact are called Chiasmata.
At chiasma, X-shaped structures are formed, where breaking and rejoining of two chromatids occur. This results in reciprocal exchange of equal and corresponding segments between them synapsis and chiasma formation are facilitated by protein filaments called synaptonemal complex.
4. Terminalisation
After crossing over, chiasma starts to move towards the terminal end of chromatids known as terminalisation. As a result, complete separation of homologous chromosomes occurs.

(i) Incomplete linkage

Rano : 1:2:1

Deletions are observable during meiotic pachytene stage and polytene chromosome. The unpaired loop formed in the normal chromosomal part at the time of chromosomal pairing. Such loops are called as deficiency loops and it can be seen in meiotic prophase.

Sharbati Sonora is a mutant variety of wheat, which is developed from Mexican variety (Sonora 64) by irradiating of gamma rays.

During zygotene stage of prophase I of meiosis I, homologous chromosomes are aligned side by side resulting in a pair of homologous chromosomes called bivalents.

Tendency of genes to remain together during separation of chromosomes is called linkage. Linkage are of 2 types - complete linkage and incomplete linkage.

Normal chromosome of Drosophila melanogaster (2n)    = 8
Trisomic condition (2n+ 1)                                                = 9
Monosomic condition (2n-l)                                              =  7

Many polyploids are more vigorous and more adaptable than diploids.
(i) Many ornamental plants are autotetraploids and have larger flower and longer flowering duration than diploids.
(ii) Autopolyploids usually have increase in fresh weight due to more water content.
(iii) Aneuploids are useful to determine the phenotypic effects of loss or gain of different chromosomes.
(iv) Many angiosperms are allopolyploids and they play a role in an evolution of plants.

Comutagens:
The compounds which are not having own mutagenic properties but can enhance the effects of known mutagens are called comutagens.
Example: Ascorbic acid increase the damage caused by hydrogen peroxide.

After tetrad formation, crossing over occurs in pachytene stage. The non-sister chromatids of homologous pair make a contact at one or more points. These points of contact between non-sister chromatids of homologous chromosomes are called Chiasmata (singular-Chiasma). At chiasma, cross-shaped or X-shaped structures are formed, where breaking and rejoining of two chromatids occur. This results in reciprocal exchange of equal and corresponding segments between them.