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Published on: 12/10/2019
Neural Control and Coordination
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1.
Distinguish between:
(a) afferent neurons and efferent neurons
(b) impulse conduction in a myelinated nerve fibre and unmyelinated nerve fibre
(f) cranial nerves and spinal nerves.
2.
Differentiate between:
(a) Myelinated and non-myelinated axons
(b) Dendrites and axons
(c) Rods and cones
(d) Thalamus and Hypothalamus
(e) Cerebrum and Cerebellum
3.
Explain the following:
(al Role of Na+ in the generation of action potential.
(b) Mechanism of generation of light-induced impulse in the retina.
(c) Mechanism through which a sound produces a nerve impulse in the inner ear.
4.
Give a brief account of Mechanism of synaptic transmission.
5.
Write short notes on the following:
(a) Neural coordination
(b) Forebrain
(c) Midbrain
(d) Hindbrain
(e) Synapse
6.
Draw labelled diagrams of the following:
(a) Neuron
(b) Brain
7.
Explain the following processes:
(a) Polarisation of the membrane of a nerve fibre
(b) Depolarisation of the membrane of a nerve fibre
(c) Transmission of a nerve impulse across a chemical synapse
8.
Compare the following:
(a) Central neural system (CNS) and Peripheral neural system (PNS)
(b) Resting potential and action potential
9.
Briefly describe the structure of the following:
(a) Brain (b) Eye (c) Ear
1.
(a) The afferent nerve fibres transmit impulses from tissues/organs to the CNS and the efferent fibres transmit regulatory impulses from the CNS to the concerned peripheral tissues/organs.
(b) The evolutionary need for the fast and efficient transduction of electrical signals in neural system resulted in appearance of myelin sheaths around neuronal axons. Myelin sheath reduces membrane capacitance and increases membrane resistance in the inter-node intervals, thus allowing a fast, saltatory movement of action potentials from node to node. Myelination is found mainly in vertebrates, but an analogous system has been discovered in a few invertebrates, such as some species of shrimp. Not all neurons in vertebrates are myelinated; for example, axons of the neurons comprising autonomous (vegetative) neural system are not myelinated in general. The conduction velocity v of myelinated neurons varies roughly linearly with axon diameter whereas the speed of unmyelinated neurons varies roughly as the square root of diameter. Myelin has two important advantages. fast \ conduction speed and energy efficiency. Also, since the ionic currents are confined to the nodes of Ranvier, there is far fewer ions "leak" across the membrane, saving metabolic energy. This saving is a significant selective advantage, since the human neural system uses approximately 20% of the body's metabolic energy.
(f) Cranial nerves are nerves that emerge directly from the brain stem in contrast to spinal nerves which emerge from segments of the spinal cord. Peripheral nerves are separated to achieve segmental innervation, cranial nerves are divided to serve one or a few specific functions in wider anatomical territories.
2.
(a) Myelinated and non-myelinated axons. The myelinated nerve fibres are enveloped with Schwann cells, which form a myelin sheath around the axon. The gaps between two adjacent myelin sheaths are called nodes of Ranvier. Myelinated nerve fibres are found in spinal and cranial nerves. Unmyelinated nerve fibre is enclosed by a Schwann cell that does not form a myelin sheath around the axon, and is commonly found in autonomous and the somatic neural systems. (b) Dendrites. Short fibres which branch repeatedly and project out of the cell body also contain Nissl's granules and are called dendrites. These fibres transmit impulses towards the cell body. Axon. The axon is a long fibre, the distal end of which is branched. Each branch terminates as a bulb-like structure called synaptic knob which possess synaptic vesicles containing chemicals called neurotransmitters. The axons transmit nerve impulses away from the cell body to a synapse or to a neuromuscular junction.
(c) Rods and Cones. There are two types of photoreceptor cells, namely, rods and cones. These cells contain the light-sensitive proteins called the photopigments. The daylight (photopic) vision and colour vision are functions of cones and the twilight (scotopic) vision is the function of the rods. The rods contain a purplish-red protein called the rhodopsin or visual purple, which contains a derivative of Vitamin A.
(d) Thalamus and Hypothalamus. The cerebrum wraps around a structure called thalamus, which is a major coordinating centre for sensory and motor signaling. Another very important part of the brain called hypothalamus lies at the base of the thalamus. The hypothalamus contains a number of centres which control body temperature, urge for eating and drinking. It also contains several groups of neurosecretory cells, which secrete hormones called hypothalamic hormones. (e) Cerebrum and Cerebellum. The cerebrum is located in the forebrain while cerebellum is located in the hind brain.
3.
(a) The sodium-potassium pump sends 3Na+ outside for every 2K+ inside the axon. This helps in maintaining a higher concentration of Na+ outside the axonal membrane. This further helps maintain the potential difference across the membrane, which is necessary for initiation of action potential.
(b) Light induces dissociation of the retinal from opsin resulting in changes in the structure of the opsin. This causes membrane permeability changes. As a result, potential differences are generated in the photoreceptor cells. This produces a signal that generates action potentials in the ganglion cells through the bipolar cells.
(c) The hollow channels of the inner ear are filled with liquid, and contain a sensory epithelium that is studded with hair cells. The microscopic "hairs" of these cells are structural protein filaments that project out into the fluid. The hair cells are mechanoreceptors that release a chemical neurotransmitter when stimulated. Sound waves moving through fluid push the filaments; if the filaments bend over enough it causes the hair cells to fire. In this way, sound waves are transformed into nerve impulses.
4.
Mechanism of synaptic transmission
Synapse is a junction between two neurons. It is present between the axon terminal of one neuron and the dendrite of next neuron separated by a cleft.
There are two ways of synaptic transmission.
(1) Chemical transmission
(2) Electrical transmission
1. Chemical transmission – When a nerve impulse reaches the end plate of axon, it releases a neurotransmitter (acetylcholine) across the synaptic cleft. This chemical is synthesized in cell body of the neuron and is transported to the axon terminal. The acetylcholine diffuses across the cleft and binds to the receptors present on the membrane of next neuron. This causes depolarization of membrane and initiates an action potential.
2. Electrical transmission – In this type of transmission, an electric current is formed in the neuron. This electric current generates an action potential and leads to transmission of nerve impulse across the nerve fibre. This represents a faster method of nerve conduction than the chemical method of transmission.
5.
(a) Neural Coordination. The functions of the organs/organ systems in our body must be coordinated to maintain homeostasis. Coordination is the process through which two or more organs interact and complement the functions of one another. For example, when we do physical exercises, the energy demand is increased for maintaining an increased muscular activity. The supply of oxygen is also increased. The increased supply of oxygen necessitates an increase in the rate of respiration, heartbeat and increased blood flow via blood vessels. When physical exercise is stopped, the activities of nerves, lungs, heart and kidney gradually return to their normal conditions. Thus, the functions of muscles, lungs, heart, blood vessels, kidney and other organs are coordinated while performing physical exercises. In our body, the neural system and the endocrine system jointly coordinate and integrate all the activities of the organs so that they function in a synchronised fashion.
(b) Forebrain. The forebrain consists of cerebrum, thalamus and hypothalamus. Cerebrum forms the major part of the human brain. A deep cleft divides the cerebrum longitudinally into two halves, which are termed as the left and right cerebral hemispheres. The hemispheres are connected by a tract of nerve fibres called corpus callosum. The cerebral cortex contains motor areas, sensory areas and large regions that are neither clearly sensory nor motor in function. These regions called as the association areas are responsible for complex functions like intersensory associations, memory and communication. The cerebrum wraps around a structure called thalamus, which is a major coordinating centre for sensory and motor signaling. Another very important part of the brain called hypothalamus lies at the base of the thalamus. The hypothalamus contains a number of centres which control body temperature, urge for eating and drinking. It also contains several groups of neurosecretory cells, which secrete hormones called hypothalamic hormones. The inner parts of cerebral hemispheres and a group of associated deep structures like amygdala, hippocampus, etc., form a complex structure called the limbic lobe or limbic system. Along with the hypothalamus, it is involved in the regulation of sexual behaviour, expression of emotional reactions (e.g., excitement, pleasure, rage and fear), and motivation.
(c) Midbrain. The midbrain is located between the thalamus/hypothalamus of the forebrain and pons of the hindbrain. Acanal called the cerebral aqueduct passes through the midbrain. The dorsal portion of the midbrain consists mainly of four round swellings (lobes) called corpora quadrigemina. Midbrain and hindbrain form the brain stem.
(d) Hindbrain. The hindbrain comprises pons, cerebellum and medulla (also called the medulla oblongata). Pons consists of fibre tracts that interconnect different regions of the brain. Cerebellum has very convoluted surface in order to provide the additional space for many more neurons. The medulla of the brain is connected to the spinal cord. The medulla contains centres which control respiration, cardiovascular reflexes and gastric secretions.
(e) Synapse. A nerve impulse is transmitted from one neuron to another through junctions called synapses. A synapse is formed by the membranes of a presynaptic neuron and a post-synaptic neuron, which may or may not be separated by a gap called synaptic cleft. There are two types of synapses, namely, electrical synapses and chemical synapses. Electrical Synapse. At electrical synapses, the membranes of pre- and postsynaptic neurons are in very close proximity. Electrical current can flow directly from one neuron into the other across these synapses. Transmission of an impulse across electrical synapses is very similar to impulse conduction along a single axon. Impulse transmission across an electrical synapse is always faster than that across a chemical synapse. Electrical synapses are rare in our system.
6.
(a) Neuron

(b) Brain

7.
a) Polarisation of the membrane of a nerve fibre. The fluid inside the membrane contains high concentration of K+and negatively charged proteins and low concentration of Na+.
In contrast, the fluid outside the axon contains a low concentration of K+, a high concentration of Na+ and thus forms a concentration gradient. These ionic gradients across the resting membrane are maintained by the active transport of ions by the sodium-potassium pump which transports 3 Na+ outwards for 2 K+ into the cell. As a result, the outer surface of the axonal membrane possesses a positive charge while its inner surface becomes negatively charged and therefore is polarised.
b) Depolarisation of the membrane of a nerve fibre. When a stimulus is applied at a site on the polarised membrane, the membrane at the site A becomes freely permeable to Na+, This leads to a rapid influx of Na+ followed by the reversal of the polarity at that site, i.e., the outer surface of the membrane becomes negatively charged and the inner side becomes positively charged. The polarity of the membrane at the site is thus reversed and hence depolarised.
c) Transmission of a nerve impulse across chemical synapse. At a chemical synapse, the membranes of the pre- and post-synaptic neurons are separated by a fluid-filled space called synaptic cleft. Chemicals called neurotransmitters are involved in the transmission of impulses at these synapses. The axon terminals contain vesicles filled with these neurotransmitters. When an impulse (action potential) arrives at the axon terminal, it stimulates the movement of the synaptic vesicles towards the membrane where they fuse with the plasma membrane and release their neurotransmitters in the synaptic cleft. The released neurotransmitters bind to their specific receptors, present on the post-synaptic membrane. This binding opens ion channels allowing the entry of ions which can generate a new potential in the postsynaptic neuron. The new potential developed may be either excitatory or inhibitory.
8.
(a) Central neural system (CNS) and Peripheral neural system (PNS)
Central neural system (CNS) :
It is the main coordinating centre of the body.
It lies inside the skull.
This includes brain and spinal cord.
Peripheral neural system (PNS) :
It is not the main coordinating centre of the body.body.
It is present outside the skull in the peripheral areas of the body.
This includes all the nerves of the bodyassociated with the CNS (brain and spinalcord).
(b) Resting potential and action potential
Resting potential :
It is the potential difference across the nerve fibrefibre when there is no conducting of nerve impulse.
The interior of the neuron is electronegative and the exterior is electropositive.
An active sodium pump operates.
Action potential :
It is the potential difference across nerve when there is conduction of nerve impulse.
The interior of the neuron is electropositive and the exterior is electronegative.
No sodium pump operates.
9.
(a) Structure of Brain.
The human brain is well protected by the skull. Inside the skull, the brain is covered by cranial meninges consisting of an outer layer called dura mater, a very thin middle layer called arachnoid and an inner layer (which is in contact with the brain tissue) called pia mater. The brain can be divided into three major parts:
(i) Forebrain, (ii) Midbrain, and (iii) Hindbrain.
(b) Structure of Eye.
In the human eye, the anterior portion is called cornea. On the cornea there is a dark spot called iris which acts like an aperture to allow optimum light inside for a better vision. The posterior portion of the eye contains the retina which acts like screen where image is focused. Retina is full of photoreceptor cells. These cells convert the light into nerve signals which are sent to the brain to make a perception of image.
(c) Structure of Ear.
Anatomically, the ear can be divided into three major sections called the outer ear, the middle ear and the Inner ear. Outer Ear. The outer ear consists of the pinna and external auditory meatus (canal). The pinna collects the vibrations in the air which produce sound. Middle Ear. The middle ear contains three ossicles called malleus, incus and stapes which are attached to one another in a chain-like fashion. These ossicles transmit sound waves further inside the ear. Inner Ear. The inner ear consists cochlea which has hair like structures. These hair like structures convert sound waves into nerve signals which are sent to the brain to make a perception of sound.
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