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Published on: 03/10/2019
Human Health and Disease
Download CBSE Class 12th Standard CBSE Biology question papers, sample papers, important questions, and previous year solved papers in PDF format. Get free study materials, NCERT solutions, and exam preparation resources for Class 12th Standard CBSE Biology
Questions + Answers key
Take MCQ Biology Test

1.
Represent schematically the life cycle of a malarial parasite.
2.
In the given flow diagram, the replication of retrovirus in a host is shown. Observe and answer the following questions.
(a) fill in (A) and (B)

b) Why is the virus called retrovirus?
(c) Can the infected cell survive, while viruses are being replicated and released?
3.
What is the mechanism by which the AIDS virus causes deficiency of immune system of the infected person?
4.
What are recombinant DNA vaccines? Give two examples of such vaccines. Discuss their advantages.
5.
After consuming sugarcane juice from a roadside vendor, Monu suffered from cough. His mother advised him to cover his nose while coughting and sneezing.
Read the above passage and answer the following questions:
(i) Why did Monu fall ill?
(ii) Why did his mother advise him to cover his nose while coughting and snazing?
6.
Answer the following questions:
(a) How are the cancer cells different from normals cells?
(b) Pick out correct carcinogens out of the following :
Asbestos, infra red rays, arsenic, polythene, casein, caffein, tobacco smoke, Gamma rays.
(c) Write down three methods (write full forms wherever required) to detect cancer of internal organs.
7.
Why is penicillin not effective in primary atypical pneumonia?
8.
What is Pulse Polio Programme of Government of India? What is OPV? Why is it that India is yet to eradicate Pollio.
9.
Why do some adolescent start taking drugs?How can this be avoided.
10.
Describe the asexual and sexual phases of life cycle of Plasmodium that causes malaria in humans.
1.
The life cycle of a malarial parasite is shown below:

2.
(a)
(b) The virus is called retro virus because its genetic material is RNA that is transcribed to DNA using enzyme reverse transciptase.
(c) Yes, the infected cell can survive, while viruses are being replicated and released.
3.
The process by which retrovirus gains entry into human host body or the mechanism by which AIDS virus causes immunodeficiency is as follows:

4.
Recombinant DNA vaccines are made up of a small circular DNA (plasmid) that has very tiny piece of pathogen DNA incorporated in it to produce one or two specific proteins of the pathogen.
This recombinant DNA is introduced into the bacteria or yeast cells, where it can use cell's machinery to produce polypetides of pathogen.
These are used as vaccines to trigger a range of immune responses. Vaccines produced by using this approach allow large scale production, e.g.
(i) Hepatits-B vaccines produced from yeast.
(ii) Bird flu DNA vaccine.
Advantages
(i) Recombinant DNA vaccines are advantageous over killed or attenuated vaccines since, they do not get virulent or mutated again as it is seen in case of attenuated vaccines.
(ii) Secondly these are highly pure, specific and elicit strong immune response.
5.
(i) He consumed uncovered food products and drinks which got contaminated by pathogenic microbes.
(ii) This practice helps in preventing spread of infectious diseases.
6.
(a)
| Cancer cells | Normal cells |
| 1. They do not undergo differentiation. | 1. They undergo differentiation |
| 2. Cancer cells undergo uncontrolled divisions | 2. Cell division are regulated |
| 3. These cells do not require extracellular growth factors. | 3. These cells require extracellular growth factors |
| 4. Cells do not remain adhered. | 4. Cells remain adhered to one another |
| 5. Cell death is inhibited. | 5. These cells have finite life span. |
| 6. These tend fo form tumour | 6. Tumours are not formed |
(b) The carcinogens are asbestos, gamma rays, tobacco smoke and arsenic.
(c) Detection and diagnosis of cancer depends upon histological features of malignant structure.
(i) Biopsy of bone marrow and abnormal count of WBCs is done in leukemia.
(ii) Pap test (cytological staining) is used for detecting cancer of cervix and other genital tract parts.
(iii) Radiography, CT scan (Computed Tomography), Magnetic Resonance Imaging (MRI scan) are useful technique to detect cancer of internal organs.
7.
Primary atypical pneumonia is a community-acquired pneumonia caused by Mycoplasma pneumoniae which lacks the cell wall.Due to absence of cell wall,it is resistant to enzymes and penicillin
8.
Pulse Polio Programme was started in 1978.Pulse Polio programme is the administration of oral Polio vaccine at regular intervals to the children under the age of five.Government provides vaccine free of cost.Many NGOs also participate with a mission to make India free of polio disease OPV is the vaccine given orally.The project 'Fight poliomyelitis' through a large cycle vaccination programme and monitoring for polio cases.F Due to this project, on march 27,2014 World Health Organization declared India a polio free country since no cause of wild polio had been reported.
9.
It is true that once a person gets entangled in the deadly whirlpool of alcohol or drugs, it is very difficult to get rid of this habit because, in the absence of a continuous supply of alcohol/drugs, the person starts showing certain symptoms called withdrawal signs which are listed below:
(1) Anxiety
(2) Shakiness
(3) Nausea
(4)Sweating.
10.
Asexual Phase
It occurs in the human host. The sporozoites enter the human body through the bite of an infected female Anopheles mosquito.
They reach the liver through blood and multiply within the liver cells.
Such liver cells burst and release the parasite into blood.
The parasite enters RBCs, multiply in them and cause their rupture.
The rupture of RBCs is associated with the release of a toxin, called haemozoin, which is responsible for the chill/shivering and the high temperature (fever) of the body. Sexual Phase
It starts with the formation of gametocytes in the RBCs of man.
The parasite then enters the female Anopheles mosquito, along with the blood when it bites the infected person.
Further development occurs in the stomach wall of mosquito.
The gametes fuse to form a zygote. The zygote undergoes further development to form sporozoites.
Sporozoites are transported to and stored in the salivary glands of the mosquito and are transferred to a human body during the bite of the mosquito.
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