The first clinical gene therapy was done for the treatment of

(a)

AIDS

(b)

Cancer

(c)

Cystic fibrosis

(d)

SCID

Dolly, the sheep was obtained by a technique known as

(a)

Cloning by gene transfer

(b)

Cloning without the help of gametes

(c)

Cloning by tissue culture of somatic cells

(d)

Cloning by nuclear transfer

The genetic defect adenosine deaminase deficiency may be cured permanently by

(a)

Enzyme replacement therapy

(b)

periodic infusion of genetically engineered lymphocytes having ADA cDNA

(c)

administering adenosine deaminase activators

(d)

introducing bone marrow cells producing ADA into embryo at an early stage of development.

How many amino acids are arranged in the two chains of Insulin

(a)

Chain A has 12 and Chain B has 13

(b)

Chain A has 21 and Chain B has 30 amino acids

(c)

Chain A has 20 and Chain B has 30 amino acids

(d)

Chain A has 12 and chain B has 20 amino acids.

PCR proceeds in three distinct steps governed by temperature, they are in order of

(a)

Denaturation, Annealing, Synthesis

(b)

Synthesis, Annealing, Denaturation

(c)

Annealing, Synthesis, Denaturation

(d)

Denaturation, Synthesis, Annealing

Which one of the following statements is true regarding DNA polymerase used in PCR?

(a)

It is used to ligate introduced DNA in recipient cells

(b)

It serves as a selectable marker

(c)

It is isolated from a Virus

(d)

It remains active at a high temperature

ELISA is mainly used for

(a)

Detection of mutations

(b)

Detection of pathogens

(c)

Selecting animals having desired traits

(d)

Selecting plants having desired traits

Transgenic animals are those which have

(a)

Foreign DNA in some of their cells

(b)

Foreign DNA in all their cells

(c)

Foreign RNA in some of their cells

(d)

Foreign RNA in all their cells

Vaccines that use components of a pathogenic organism rather than the whole organism are called

(a)

Subunit recombinant vaccines

(b)

attenuated recombinant vaccines

(c)

DNA vaccines

(d)

conventional vaccines