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12th Standard Biology - Zoology - Molecular Genetics Model Question Paper Oct-09 , 2019

Zoology - Molecular Genetics 

12th Standard Biology - Zoology - Molecular Genetics Model Question Paper

Zoology - Molecular Genetics Model Question Paper

12th Standard

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Biology

Time : 02:00:00 Hrs
Total Marks : 60
    8 x 1 = 8

  1. Hershey and Chase experiment with bacteriophage showed that ______.

    (a)

    Protein gets into the bacterial cells

    (b)

    DNA is the genetic material

    (c)

    DNA contains radioactive sulphur

    (d)

    Viruses undergo transformation

  2. What is the basis for the difference in the synthesis of the leading and lagging strand of DNA molecules?

    (a)

    Origin of replication occurs only at the 5' end of the molecules

    (b)

    DNA ligase works only in the 3' → 5' direction

    (c)

    DNA polymerase can join new nucleotides only to the 3' end of the growing stand.

    (d)

    Helicases and single-strand binding proteins that work at the 5' end

  3. The first codon to be deciphered was ______ which codes for ________.

    (a)

    AAA, proline

    (b)

    GGG, alanine

    (c)

    UUU, Phenylalanine

    (d)

    TTT, arginine

  4. When lactose is present in the culture medium:

    (a)

    Transcription of lac y, lac z, lac a genes occurs.

    (b)

    Repressor is unable to bind to the operator.

    (c)

    Repressor is able to bind to the operator.

    (d)

    Both (a) and (b) are correct.

  5. One gene one enzyme hypothesis was proposed by Beadle and Tatum based on ________

    (a)

    Yeast

    (b)

    Drosophila

    (c)

    E. coli

    (d)

    Neurospora

  6. Human Genome was sequenced in ________.

    (a)

    1979

    (b)

    2015

    (c)

    1989

    (d)

    2001

  7. The term ___________ refers to DNA of Prokaryotes.

    (a)

    Nuclein

    (b)

    Ribozyme

    (c)

    Genophore

    (d)

    Nucleosome

  8. The Okazaki segments are joined by _________.

    (a)

    DNA polymerase

    (b)

    RNA polymerase

    (c)

    DNA ligase

    (d)

    Endonuclease

    9. 5 x 1 = 5

  9. Kornberg enzyme is called as _________

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    DNA polymerase I

  10. Goldberg - Hogness box of eukaryotes is equivalent to__________ of prokaryotes.

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    Pribnow box

  11. __________ number of codons, codes for cystine

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    Two

  12. _____________ is the monomer of DNA.

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    Nucleotide

    13. 5 x 1 = 5

  13. SNPs

    14. (1)

    Snips

  14. Initiation complex

    15. (2)

    Charging of tRNA

  15. Semi-conservative model

    16. (3)

    GTP

  16. Aminoacyl synthetase

    17. (4)

    Meselson and Stahl

  17. UGA

    18. (5)

    Tyrosine
    2 x 2 = 4

  18. Assertion: The tRNA decodes the information on mRNA.
    Reason: It has an extra arm.
    Codes:
    A. A and R are true, Ris the correct explanation of A
    B. A and R are true, R is not the correct explanation of A
    C. A is true, R is false
    D. Both A and R are false

  19. Assertion: Both the strands of DNA can be copied during transcription.
    Reason: This will help to produce more RNA with different sequences
    Codes:
    A. A and R are true, Ris the correct explanation of A
    B. A and R are true, R is not the correct explanation of A
    C. A is true, R is false
    D. Both A and R are false

    20. 4 x 1 = 4

  20. There are no tRNA for stop codons.

  21. PCR is an important part of DNA finger printing technique.

  22. The genetic code is said to be Non-ambiguous.

  23. The triplet codon is described as 'degenerate code'.

    24. 6 x 2 = 12

  24. Give reasons: ‘Genetic code is universal’.

  25. Differentiate - Leading stand and lagging strand

  26. Mention any two ways in which single nucleotide polymorphism (SNPs) identified in human genome can bring revolutionary change in biological and medical science.

  27. State any three goals of the human genome project.

  28. What is a nucleosomer?

  29. Expand and define NHC

    30. 4 x 3 = 12

  30. Distinguish between structural gene, regulatory gene and operator gene

  31. A low level of expression of lac operon occurs at all the windows for treatment of various genetic disorders. Justify the statement

  32. From their examination of the structure of DNA, What did Watson and Crick infer about the probable mechanism of DNA replication, coding capability and mutation?

  33. Differentiate DNA and RNA.

    34. 2 x 5 = 10

  34. a) Identify the figure given below
    b) Redraw the structure as a replicating fork and label the parts
    c) Write the source of energy for this replication and name the enzyme involved in this process.
    d) Mention the differences in the synthesis of protein, based on the polarity of the two template strands.

  35. Explain the formation of a nucleosome.

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