Zoology - Molecular Genetics Book Back Questions

12th Standard EM

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Biology

Time : 00:45:00 Hrs
Total Marks : 30
    5 x 1 = 5
  1. Hershey and Chase experiment with bacteriophage showed that

    (a)

    Protein gets into the bacterial cells

    (b)

    DNA is the genetic material

    (c)

    DNA contains radioactive sulphur

    (d)

    Viruses undergo transformation

  2. What is the basis for the difference in the synthesis of the leading and lagging strand of DNA molecules?

    (a)

    Origin of replication occurs only at the 5' end of the molecules

    (b)

    DNA ligase works only in the 3' → 5' direction

    (c)

    DNA polymerase can join new nucleotides only to the 3' end of the growing stand.

    (d)

    Helicases and single-strand binding proteins that work at the 5' end

  3. Which of the following is the correct sequence of event with reference to the central dogma?

    (a)

    Transcription, Translation, Replication

    (b)

    Transcription, Replication, Translation

    (c)

    Duplication, Translation, Transcription

    (d)

    Replication, Transcription, Translation

  4. Which of the following statements about DNA replication is not correct?

    (a)

    Unwinding of DNA molecule occurs as hydrogen bonds break.

    (b)

    Replication occurs as each base is paired with another exactly like it

    (c)

    Process is known as semi conservative replication because one old strand is conserved in the new molecule.

    (d)

    Complementary base pairs are held together with hydrogen bonds

  5. Meselson and Stahl’s experiment proved

    (a)

    Transduction

    (b)

    Transformation

    (c)

    DNA is the genetic material

    (d)

    Semi-conservative nature of DNA replication

  6. 3 x 2 = 6
  7. Mention any two ways in which single nucleotide polymorphism (SNPs) identified in human genome can bring revolutionary change in biological and medical science

  8. State any three goals of the human genome project.

  9. In E.coli, three enzymes β- galactosidase, permease and transacetylase are produced in the presence of lactose. Explain why the enzymes are not synthesized in the absence of lactose.

  10. 3 x 3 = 9
  11. Why tRNA is called an adapter molecule?

  12. What are the three structural differences between RNA and DNA?

  13. Name the anticodon required to recognize the following codons: AAU, CGA, UAU, and GCA.

  14. 2 x 5 = 10
  15. Why did Hershey and Chase use radioactively labelled phosphorous and sulphur only? Would they have got the same result if they use radiolabelled carbon and nitrogen?

  16. Explain the formation of a nucleosome.

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